Leveraging next-gen sequencing technologies and bench-top approaches to improve our ability to predict success in performance and recovery will support all individuals undergoing tremendous, complex, and diverse stress everyday.

We are investigating the following aims in military-focused studies:

1. Quantify genome-wide changes in gene expression that distinguish non-stressed from stressed states.

2. Quantify genome-wide changes in gene expression that distinguish successful recovery from prolonged effects of stress and are related to functional outcomes.

3. Discover biomarkers that predict the effects of acute, repeated, and chronic stress on functional outcomes in the immune system.

4. Establish predictive models that incorporate core, sensitive markers of how stress negatively impacts the immune system, physical performance, and overall health.